Berand Ltd. provides high-value preclinical drug screening services and animal models of diseases to major pharma. The company is located in NovaUCD Business Park and has access to core technologies at UCD Conway Institute. R&D in Berand relates to autism and obesity.

Products & Services
Berand’s principal activity is the delivery of outsourcing needs of major multinational pharmaceutical companies in the following areas:
• Characterisation/ proof-of-concept studies.
• Value enhancement of potential drug candidates at the preclinical/ early clinical stage of development.
• Berand has unique animal models to determine therapeutic potential for the treatment of neurological and psychiatric disease.
• Research activity focused on identifying and developing novel therapeutic targets, specifically in the fields of autism and obesity.

Clients
Partnering with or service provision to: Major multinational pharmaceutical companies, Biotechnology companies, SME’s and Research institutes.

Standards & Certifications
Licenced by the Irish Department of Health and with experimental governance by University College Dublin.

Additional Languages
German, Dutch, Irish.

Contact Name / Title
Andrew Foley, Director

Email andrew.foley@berand.ie

Web www.berand.ie

Tel +353 1 7163540 / 7163542

Address
NovaUCD, Belfield Innovation Park, Dublin 4

BioAtlantis is involved in the research, manufacture and distribution of products for the following areas (1) Biostimulant products – plant sector, stimulating natural defence systems within the plant (2) Feed additive products – targeted at post-weaning piglets and broilers.

Products & Services
• GutCare: Patented combination of two active biomolecules which modulate gastrointestinal health in the post-weaning piglet and is a replacement for growth promoting antibiotics. This allows increased feed intake and increased average daily gain leading to decreased morbidity/mortality. Other benefits include reduction in diarrhoea scores and incidence of morbidity and mortality.

Clients
Pig and poultry compounders with special emphasis on compounders producing diets for the post weaned piglet.

Standards & Certifications
Irish Department of Agriculture approved, Organic Trust and OMRI (Organic materials review institute) registration.

Additional Languages
Spanish, French.

Note
PCT has been filed and national applications have been completed for Europe and the US.

Contact Name / Title
John T. O’Sullivan, CEO

Email jtos@bioatlantis.com

Web www.bioatlantis.com

Tel +353 66 7118477

Address
Kerry Technology Park, Tralee, Co. Kerry.

EnBIO is a surface modification company that has developed a unique, market disruptive coating process for medical implant devices. This patent pending ‘active coating’ technology enriches the biocompatibility of widely used medical implant devices.

Products & Services
• CoBlast: New and novel process for applying passive and active (drug-eluting) coatings to implantable metals at room temperature, without the need for a polymer carrier or a complex application process.
• CoBlast: Can be used to apply therapeutic agents of choice to a metallic medical implant surface (e.g. antibiotic, anti-thrombotic, bone morphogenic proteins, etc).
• CoBlast: enables significantly enhanced surface-finish characteristics with superior end-product quality at a dramatically reduced application cost base with the elimination of infection and biofilm growth.

Clients
EnBio’s target customers are implant device manufacturers who will license the technology from the company.

Contact Name / Title
Dan Philpott, CEO

Email info@enbiomaterials.com

Web www.enbiomaterials.com

Tel +353 21 4882655

Address Fota Point Enterprise Park, Carrigtwohill, Co. Cork.

FastForm Research focuses on the development and commercialisation of ‘smart polymer’ technologies and superior medical products for the healthcare industry targeting a number of sectors focusing on the orthopaedics market.

Products & Services
 • Custom mouldable therapeutic solutions in the form of innovative custom mouldable splints; casts and braces. 
• Patient comfort is greatly enhanced while procedure times and associated costs are significantly reduced, thereby providing cost savings for healthcare organisations, payers and patients.

Clients
FastForm reaches markets through one of the largest global distributors in bracing and soft-goods, and sells its products in the US and in more than 50 countries worldwide.

Standards & Certifications
All quality design and development work is carried out in accordance with ISO 13485 and FDA quality systems regulation CFR21 part 820. Products are CE Marked per MDD/93/42/EEC.

Additional Languages
Polish

Note
Having one of the largest distribution networks for non-operative orthopaedic products together with strong relationships with orthopaedic professionals will greatly enhance FastForm’s market penetration and share.

Contact Name / Title
David Sheehan, Managing Director

Email d.sheehan@fastformresearch.com

Web www.fastfromresearch.com

Tel +353 51 306912

Address
Unit 4 Lear Avenue, Airport Business Park, Killowen, Co. Waterford.

IdentiGEN is a leading provider of innovative DNA-based branding solutions for whole chain traceability to the agriculture and food industries. Genetic identification, is being deployed to enhance consumer confidence in the safety and quality of food products.

Products & Services
• DNA TraceBack system: Provides traceability of meat products from point of sale to animal of origin. IdentiGEN’s tracing website www.DNAtraceback.com, provides the tools to unequivocally trace the identity of meat back to its source.
• Authentication and validation of meat product attributes such as natural, organic or Angus.
• IdentiGEN’s traceability is also used as a monitoring tool, ensuring that only meat from animals that meet customer specifications is sold in stores.

Clients
Meat packers, processors, grocery retailers and Government bodies.

Standards & Certifications
ISO 9001:2000, USDA Process Verified Programme, ISO 17025.

Additional Languages
Italian, French.

Contact Name / Title
Ciaran Meghen, Managing Director

Email info@identigen.com

Web www.identigen.com

Tel + 353 1 6770221

Address
Unit 2, Trinity Technology and Enterprise Campus, Pearse Street, Dublin 2.

Opsona Therapeutics is a leading drug development company specialising in modulating the human innate immune system to treat autoimmune and inflammatory conditions, cancers and infectious diseases. Opsona’s efforts are focussed on the role of Toll-Like Receptors (TLRs) and inflammasome signalling in human immunology and disease.

Products & Services
• OPN-305: Monoclonal antibody developed to reduce pro-inflammatory cytokine production associated with heart and kidney diseases and expected to enter the clinic in late 2010.
• Inflammasome: Small molecule programme aimed at inhibiting IL-1 β production that is associated with inflammatory diseases.
• OPN-401: Peptide capable of disabling TLR signalling pathways involved in acute and chronic inflammatory diseases.
• OPN-302: Soluble protein TLR antagonist secured through an exclusive in-license from Nestlé
• OPN-501: Oral prodrug for the treatment of ulcerative colitis
• OpsoVac: Novel TLR platform: increased efficacy and antigen sparing of vaccines and immunotherapeutics.

Clients
Wyeth, Schering-Plough, CSL Ltd and Trinity College Dublin.

Additional Languages
French, German, Italian

Note
Opsona have raised a total of €28M in Venture Capital funding and has also received additional financing through partnering and Irish Government grants to advance its research and development efforts.

Contact Name / Title
Mark Heffernan, CEO

Email heffernan@opsona.com

Web www.opsona.com

Tel +353 1 8968499

Address
Institute of Molecular Medicine, Trinity Centre for Health Sciences, St. James’ Hospital, Dublin 8.

Pharmatrin is a drug discovery and early drug development company specialising in developing small-molecule new chemical entities (NCEs) with potential therapeutic applications in the areas of inflammation and auto-immune disease.

Products & Services
• Pharmatrin focuses on small molecule NCE synthesis in discovery phase and have progressed a number of drug candidate molecules from discovery to lead optimisation and pre-clinical development.
• Developmental Pipeline: Made up of additional therapeutic targets for our lead compounds, as well as additional NCEs for use in the areas of inflammation and autoimmune disease.
• Ethnomedicine and Natural Product Chemistry: Basis to give direction and lead to small molecule synthesis of NCEs with novel biological activity, together with their assessment on a variety of cell systems in vitro and animal models in vivo.

Additional Languages
German, Italian.

Contact Name / Title
Neil Frankish, CEO

Email info@pharmatrin.com

Web www.pharmatrin.com

Tel +353 1 6709865

Address
The Tower, Trinity Technology and Enterprise Campus, Pearse Street
Dublin 2.

Sigmoid Pharma is a pharmaceutical product and drug delivery company with a portfolio of innovative orally administered gastro-intestinal disease, transplantation and neuro-degeneration products. They are enabled using proprietary LEDDS and SmPill technologies. Sigmoid collaborates with leading international academic and clinical centres.

Products & Services
• Strategic Partnerships: With pharmaceutical companies to expedite development of new and extend the life cycle of existing molecules. 
• LEDDS and SmPill: Enhance the solubility, permeability and release profile of poorly soluble APIs or to reposition drugs.
• LEDDS and SmPill: Enable paediatric and geriatric friendly formulation development.
• Sigmoid develops improved or repositioned proprietary formulations in the therapeutic areas of gastro-intestinal, transplantation and neuro-degeneration diseases, including a focus on orphan diseases.
• Product entering a Phase II study: Ulcerative colitis, Sigmoid seeks to establish strategic partnerships for these pipeline products.

Clients
Pharmaceutical companies interested in establishing strategic partnerships for the further development and commercialisation of Sigmoid’s pipeline products and also proprietary products requiring enhancemed solubility, permeability and controlled release. LEDDS and SmPill are also applicable to improve delivery of functional food ingredients.

Standards & Certifications
Licensed by the Irish Medicines Board: Sigmoid can rapidly develop formulations as well as manufacture and test clinical trial supplies in the company’s in-house GMP facilities.

Additional Languages
French, German, Polish, Portuguese, Italian.

Contact Name / Title
Ivan S. Coulter, CEO

Email info@sigmoidpharma.com

Web www.sigmoidpharma.com

Tel +353 1 7007511

Address
The Invent Centre, Dublin City University, Dublin 9.

Alimentary Health is a specialty biotechnology company focussing on developing probiotic-based healthcare and prescription drug products for management of inflammatory and infectious disease, as well as developing clinically proven bacterial strains founded on world-class scientific research.

Products & Services
• Strong pipeline fully underpinned by exclusive first negotiation option on probiotic-based technology generated by world-renowned Irish Government funded Alimentary Pharmabiotic Centre (APC).
• Partnership with Procter and Gamble has resulted in the launch of Align for the management of digestive conditions. The active component of Align is the AH proprietary strain Bif 35624.
• Procter and Gamble Pet Care has launched Prostora Max, a new probiotic supplement for dogs, developed from AH proprietary pet care probiotic technology under license.

Clients
Procter and Gamble healthcare Division, Procter and Gamble Animal healthcare, BMS – Mead Johnson, ConVatec and General Mills.

Standards & Certifications Technology validated by extensive publication in leading industry journals. Robust IP strategy with significant number of patents filed in key Patent and Trademark Office (PTO) countries.

Note
Article in Forbes magazine of 27 Oct 2008 at: www.forbes.com/claytonchristensen/forbes/2008/1027/097.html.

Contact Name / Title
Brian Barrett, CFO

Email bbarrett@ahealth.ie

Web www.alimentaryhealth.ie

Tel +353 21 4299104

Address Building 2800, Cork Airport Business Park, Kinsale Road, Cork

Arrotek offers a range of development and manufacturing services from initial product assessment through to the provision of sterile finished product.

Products & Services
• Contract medical device design and development service.
• Prototyping of concepts for product evaluation.
• Compiling and submitting for CE and FDA regulatory approval.
• Precision manufacture and supply of sterile product.

Clients
Start-up companies, University spin-outs and Innovative medical professionals developing new medical products.

Standards & Certifications
ISO 13485:2003

Contact Name / Title
Ger O’Carroll, Managing Director

Email ger@arrotek.com

Web www.arrotek.com

Tel +353 71 9122023

Address
Unit 5, Airport Part, Strandhill, Co. Sligo